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Dynamic changes of MMP-9 plasma levels correlate with JCV reactivation and immune activation in natalizumab-treated multiple sclerosis patients

The aim of the study was to investigate the changes of matrix metalloproteinase (MMP)-2 and MMP-9 plasma levels during natalizumab treatment and their correlation with JC virus (JCV) reactivation and T-lymphocyte phenotypic modifications in peripheral blood samples from 34 relapsing-remitting multip...

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Detalles Bibliográficos
Autores principales: Iannetta, Marco, Zingaropoli, Maria Antonella, Latronico, Tiziana, Pati, Ilaria, Pontecorvo, Simona, Prezioso, Carla, Pietropaolo, Valeria, Cortese, Antonio, Frontoni, Marco, D’Agostino, Claudia, Francia, Ada, Vullo, Vincenzo, Mastroianni, Claudio Maria, Liuzzi, Grazia Maria, Ciardi, Maria Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342994/
https://www.ncbi.nlm.nih.gov/pubmed/30670793
http://dx.doi.org/10.1038/s41598-018-36535-5