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A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations
Tumour sequencing identifies highly recurrent point mutations in cancer driver genes, but rare functional mutations are hard to distinguish from large numbers of passengers. We developed a novel computational platform applying a multi-modal approach to filter out passengers and more robustly identif...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343001/ https://www.ncbi.nlm.nih.gov/pubmed/30670742 http://dx.doi.org/10.1038/s41598-018-36401-4 |