The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

The circadian clock regulates immune responses to microbes and affects pathogen replication, but the underlying molecular mechanisms are not well understood. Here we demonstrate that the circadian components BMAL1 and REV-ERBα influence several steps in the hepatitis C virus (HCV) life cycle, includ...

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Detalles Bibliográficos
Autores principales: Zhuang, Xiaodong, Magri, Andrea, Hill, Michelle, Lai, Alvina G., Kumar, Abhinav, Rambhatla, Srinivasa Bhargav, Donald, Claire L., Lopez-Clavijo, Andrea F., Rudge, Simon, Pinnick, Katherine, Chang, Wai Hoong, Wing, Peter A. C., Brown, Ryan, Qin, Ximing, Simmonds, Peter, Baumert, Thomas F., Ray, David, Loudon, Andrew, Balfe, Peter, Wakelam, Michael, Butterworth, Sam, Kohl, Alain, Jopling, Catherine L., Zitzmann, Nicole, McKeating, Jane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343007/
https://www.ncbi.nlm.nih.gov/pubmed/30670689
http://dx.doi.org/10.1038/s41467-019-08299-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343007/
https://www.ncbi.nlm.nih.gov/pubmed/30670689
http://dx.doi.org/10.1038/s41467-019-08299-7

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