Combined antitumoral effects of pretubulysin and methotrexate

Pretubulysin (PT), a potent tubulin‐binding antitumoral drug, and the well‐established antimetabolite methotrexate (MTX) were tested separately or in combination (PT+MTX) for antitumoral activity in L1210 leukemia cells or KB cervix carcinoma cells in vitro and in vivo in NMRI‐nu/nu tumor mouse mode...

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Detalles Bibliográficos
Autores principales: Kern, Sarah, Truebenbach, Ines, Höhn, Miriam, Gorges, Jan, Kazmaier, Uli, Zahler, Stefan, Vollmar, Angelika M., Wagner, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343018/
https://www.ncbi.nlm.nih.gov/pubmed/30693087
http://dx.doi.org/10.1002/prp2.460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343018/
https://www.ncbi.nlm.nih.gov/pubmed/30693087
http://dx.doi.org/10.1002/prp2.460

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