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Acetaldehyde Induces Neurotoxicity In Vitro via Oxidative Stress- and Ca(2+) Imbalance-Mediated Endoplasmic Reticulum Stress
Excessive drinking can damage brain tissue and cause cognitive dysfunction. Studies have found that the early stage of neurodegenerative disease is closely related to heavy drinking. Acetaldehyde (ADE) is the main toxic metabolite of alcohol. However, the exact mechanisms of ADE-induced neurotoxicit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343137/ https://www.ncbi.nlm.nih.gov/pubmed/30728884 http://dx.doi.org/10.1155/2019/2593742 |