Acetaldehyde Induces Neurotoxicity In Vitro via Oxidative Stress- and Ca(2+) Imbalance-Mediated Endoplasmic Reticulum Stress

Excessive drinking can damage brain tissue and cause cognitive dysfunction. Studies have found that the early stage of neurodegenerative disease is closely related to heavy drinking. Acetaldehyde (ADE) is the main toxic metabolite of alcohol. However, the exact mechanisms of ADE-induced neurotoxicit...

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Detalles Bibliográficos
Autores principales: Cui, Jiahui, Liu, Yang, Chang, Xing, Gou, Wenfeng, Zhou, Xuejiao, Liu, Zi, Li, Zengqiang, Wu, Yingliang, Zuo, Daiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343137/
https://www.ncbi.nlm.nih.gov/pubmed/30728884
http://dx.doi.org/10.1155/2019/2593742

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