Age-Related Seroprevalence of Antibodies Against AAV-LK03 in a UK Population Cohort

Recombinant adeno-associated virus (rAAV) vectors are a promising platform for in vivo gene therapy. The presence of neutralizing antibodies (Nab) against AAV capsids decreases cell transduction efficiency and is a common exclusion criterion for participation in clinical trials. Novel engineered cap...

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Detalles Bibliográficos
Autores principales: Perocheau, Dany P., Cunningham, Sharon C., Lee, Juhee, Antinao Diaz, Juan, Waddington, Simon N., Gilmour, Kimberly, Eaglestone, Simon, Lisowski, Leszek, Thrasher, Adrian J., Alexander, Ian E., Gissen, Paul, Baruteau, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343184/
https://www.ncbi.nlm.nih.gov/pubmed/30027761
http://dx.doi.org/10.1089/hum.2018.098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343184/
https://www.ncbi.nlm.nih.gov/pubmed/30027761
http://dx.doi.org/10.1089/hum.2018.098

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