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Nucleocytoplasmic distribution of S6K1 depends on the density and motility of MCF-7 cells in vitro

Background: The ribosomal protein S6 kinase 1 (S6K1) is one of the main components of the mTOR/S6K signal transduction pathway, which controls cellular metabolism, autophagy, growth, and proliferation. Overexpression of S6K1 was detected in tumors of different origin including breast cancer, and cor...

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Detalles Bibliográficos
Autores principales: Kosach, Viktoriia, Shkarina, Kateryna, Kravchenko, Anastasiia, Tereshchenko, Yuliia, Kovalchuk, Evelina, Skoroda, Larysa, Krotevych, Mykhailo, Khoruzhenko, Antonina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343231/
https://www.ncbi.nlm.nih.gov/pubmed/30705751
http://dx.doi.org/10.12688/f1000research.15447.2