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Monoclonal antibody against EV71 3D(pol) inhibits the polymerase activity of RdRp and virus replication

BACKGROUND: Enterovirus A 71 (EV71) is a neurotropic virus that may lead to acute flaccid paralysis, encephalitis, cardiopulmonary failure or even death. No vaccine and defensive drug controlling EV71 is currently available, novel and efficient antiviral drug or vaccine is therefore urgently needed....

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Detalles Bibliográficos
Autores principales: Li, Yaoming, Yu, Jie, Qi, Xiuwen, Yan, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343263/
https://www.ncbi.nlm.nih.gov/pubmed/30669993
http://dx.doi.org/10.1186/s12865-019-0288-x