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Monoclonal antibody against EV71 3D(pol) inhibits the polymerase activity of RdRp and virus replication
BACKGROUND: Enterovirus A 71 (EV71) is a neurotropic virus that may lead to acute flaccid paralysis, encephalitis, cardiopulmonary failure or even death. No vaccine and defensive drug controlling EV71 is currently available, novel and efficient antiviral drug or vaccine is therefore urgently needed....
Autores principales: | Li, Yaoming, Yu, Jie, Qi, Xiuwen, Yan, Huimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343263/ https://www.ncbi.nlm.nih.gov/pubmed/30669993 http://dx.doi.org/10.1186/s12865-019-0288-x |
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