Human double negative T cells target lung cancer via ligand-dependent mechanisms that can be enhanced by IL-15

BACKGROUND: The advents of novel immunotherapies have revolutionized the treatment of cancer. Adoptive cellular therapies using chimeric antigen receptor T (CAR-T) cells have achieved remarkable clinical responses in B cell leukemia and lymphoma but the effect on solid tumors including lung cancer i...

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Detalles Bibliográficos
Autores principales: Yao, Junlin, Ly, Dalam, Dervovic, Dzana, Fang, Linan, Lee, Jong Bok, Kang, Hyeonjeong, Wang, Yu-Hui, Pham, Nhu-An, Pan, Hongming, Tsao, Ming-Sound, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343266/
https://www.ncbi.nlm.nih.gov/pubmed/30670085
http://dx.doi.org/10.1186/s40425-019-0507-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343266/
https://www.ncbi.nlm.nih.gov/pubmed/30670085
http://dx.doi.org/10.1186/s40425-019-0507-2

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