HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer

BACKGROUND: Tumour hypoxia is a driver of breast cancer progression associated with worse prognosis and more aggressive disease. The cellular response to hypoxia is mediated by the hypoxia-inducible transcription factors HIF-1 and HIF-2, whose transcriptional activity is canonically regulated throug...

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Detalles Bibliográficos
Autores principales: Jarman, Edward J., Ward, Carol, Turnbull, Arran K., Martinez-Perez, Carlos, Meehan, James, Xintaropoulou, Chrysi, Sims, Andrew H., Langdon, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343358/
https://www.ncbi.nlm.nih.gov/pubmed/30670058
http://dx.doi.org/10.1186/s13058-019-1097-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343358/
https://www.ncbi.nlm.nih.gov/pubmed/30670058
http://dx.doi.org/10.1186/s13058-019-1097-0

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