The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis

The pathogenesis of SpA is multifactorial and involves a range of immune cell types and cytokines, many of which utilize Janus kinase (JAK) pathways for signaling. In this review, we summarize the animal and pre-clinical data that have demonstrated the effects of JAK blockade on the underlying molec...

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Detalles Bibliográficos
Autores principales: Veale, Douglas J, McGonagle, Dennis, McInnes, Iain B, Krueger, James G, Ritchlin, Christopher T, Elewaut, Dirk, Kanik, Keith S, Hendrikx, Thijs, Berstein, Gabriel, Hodge, Jennifer, Telliez, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343466/
https://www.ncbi.nlm.nih.gov/pubmed/29618084
http://dx.doi.org/10.1093/rheumatology/key070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343466/
https://www.ncbi.nlm.nih.gov/pubmed/29618084
http://dx.doi.org/10.1093/rheumatology/key070

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