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Optic Nerve Head Astrocytes Display Axon-Dependent and -Independent Reactivity in Response to Acutely Elevated Intraocular Pressure

PURPOSE: Optic nerve head (ONH) astrocytes provide support for axons, but exhibit structural and functional changes (termed reactivity) in a number of glaucoma models. The purpose of this study was to determine if ONH astrocyte structural reactivity is axon-dependent. METHODS: Using rats, we combine...

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Detalles Bibliográficos
Autores principales: Tehrani, Shandiz, Davis, Lauren, Cepurna, William O., Delf, R. Katherine, Lozano, Diana C., Choe, Tiffany E., Johnson, Elaine C., Morrison, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343680/
https://www.ncbi.nlm.nih.gov/pubmed/30665231
http://dx.doi.org/10.1167/iovs.18-25447