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Next-generation sequencing reveals mutational accordance between cell-free DNA from plasma, malignant pleural effusion and ascites and directs targeted therapy in a gastric cancer patient

Cell-free DNA (cfDNA) has been a research hotspot in molecular tumor profiling. In advanced gastric cancer patients, malignant pleural effusion (MPE) and ascites provide a wealth of tumor cells that can be investigated. Here we conducted next-generation sequencing (NGS) on matched cfDNA from plasma,...

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Detalles Bibliográficos
Autores principales: Zhou, Shujuan, Xu, Bo, Qi, Liang, Zhu, Dongqin, Liu, Baorui, Wei, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343684/
https://www.ncbi.nlm.nih.gov/pubmed/30118648
http://dx.doi.org/10.1080/15384047.2018.1504720