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The positive circadian regulators CLOCK and BMAL1 control G2/M cell cycle transition through Cyclin B1

We previously identified a tight bidirectional phase coupling between the circadian clock and the cell cycle. To understand the role of the CLOCK/BMAL1 complex, representing the main positive regulator of the circadian oscillator, we knocked down Bmal1 or Clock in NIH3T3(3C) mouse fibroblasts (carry...

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Detalles Bibliográficos
Autores principales: Farshadi, Elham, Yan, Jie, Leclere, Pierre, Goldbeter, Albert, Chaves, Inês, van der Horst, Gijsbertus T. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343743/
https://www.ncbi.nlm.nih.gov/pubmed/30558467
http://dx.doi.org/10.1080/15384101.2018.1558638