FGFR1β is a driver isoform of FGFR1 alternative splicing in breast cancer cells

Abnormal FGFR1 alternative splicing is correlated with tumorigenicity and poor prognosis in several tumor types. We sought to determine the roles of FGFR1α and FGFR1β variants in breast cancer. TCGA samples and cell lines were analyzed for FGFR1α/FGFR1β expression. MCF-10A cells were used to overexp...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Zhuo, Ming-Lei, Zheng, Xiaofeng, Su, Xiaoping, Meric-Bernstam, Funda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343755/
https://www.ncbi.nlm.nih.gov/pubmed/30713601
http://dx.doi.org/10.18632/oncotarget.26530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343755/
https://www.ncbi.nlm.nih.gov/pubmed/30713601
http://dx.doi.org/10.18632/oncotarget.26530

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