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FGFR1β is a driver isoform of FGFR1 alternative splicing in breast cancer cells
Abnormal FGFR1 alternative splicing is correlated with tumorigenicity and poor prognosis in several tumor types. We sought to determine the roles of FGFR1α and FGFR1β variants in breast cancer. TCGA samples and cell lines were analyzed for FGFR1α/FGFR1β expression. MCF-10A cells were used to overexp...
Autores principales: | Zhao, Ming, Zhuo, Ming-Lei, Zheng, Xiaofeng, Su, Xiaoping, Meric-Bernstam, Funda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343755/ https://www.ncbi.nlm.nih.gov/pubmed/30713601 http://dx.doi.org/10.18632/oncotarget.26530 |
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