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Comprehensive characterization of monoclonal antibody by Fourier transform ion cyclotron resonance mass spectrometry

The pharmaceutical industry’s interest in monoclonal antibodies (mAbs) and their derivatives has spurred rapid growth in the commercial and clinical pipeline of these effective therapeutics. The complex micro-heterogeneity of mAbs requires in-depth structural characterization for critical quality at...

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Detalles Bibliográficos
Autores principales: Jin, Yutong, Lin, Ziqing, Xu, Qingge, Fu, Cexiong, Zhang, Zhaorui, Zhang, Qunying, Pritts, Wayne A., Ge, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343775/
https://www.ncbi.nlm.nih.gov/pubmed/30230956
http://dx.doi.org/10.1080/19420862.2018.1525253