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Comprehensive characterization of monoclonal antibody by Fourier transform ion cyclotron resonance mass spectrometry
The pharmaceutical industry’s interest in monoclonal antibodies (mAbs) and their derivatives has spurred rapid growth in the commercial and clinical pipeline of these effective therapeutics. The complex micro-heterogeneity of mAbs requires in-depth structural characterization for critical quality at...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343775/ https://www.ncbi.nlm.nih.gov/pubmed/30230956 http://dx.doi.org/10.1080/19420862.2018.1525253 |