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Generation by phage display and characterization of drug-target complex-specific antibodies for pharmacokinetic analysis of biotherapeutics
Anti-idiotypic antibodies play an important role in pre-clinical and clinical development of therapeutic antibodies, where they are used for pharmacokinetic studies and for the development of immunogenicity assays. By using an antibody phage display library in combination with guided in vitro select...
Autores principales: | Harth, Stefan, Ten Haaf, Andre, Loew, Christian, Frisch, Christian, Knappik, Achim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343800/ https://www.ncbi.nlm.nih.gov/pubmed/30516449 http://dx.doi.org/10.1080/19420862.2018.1538723 |
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