Combination of immunogenic oncolytic adenovirus ONCOS-102 with anti-PD-1 pembrolizumab exhibits synergistic antitumor effect in humanized A2058 melanoma huNOG mouse model

Malignant melanoma is an aggressive type of skin cancer whose incidence is increasing globally. Although surgery is effective in early stage melanoma, patients with advanced melanoma only have a 20% 5-year survival rate. Hence, combinations of existing and new immunotherapy technologies and immunoth...

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Detalles Bibliográficos
Autores principales: Kuryk, Lukasz, Møller, Anne-Sophie W., Jaderberg, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343802/
https://www.ncbi.nlm.nih.gov/pubmed/30713786
http://dx.doi.org/10.1080/2162402X.2018.1532763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343802/
https://www.ncbi.nlm.nih.gov/pubmed/30713786
http://dx.doi.org/10.1080/2162402X.2018.1532763

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