Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5

Although the proteasome inhibitor bortezomib has significantly improved the survival of patients with multiple myeloma (MM), the disease remains fatal as most patients eventually develop progressive disease. Recent data indicate that MM cells can evade bortezomib-induced cell death by undergoing aut...

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Detalles Bibliográficos
Autores principales: Carlsten, Mattias, Namazi, Ali, Reger, Robert, Levy, Emily, Berg, Maria, St. Hilaire, Cynthia, Childs, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343814/
https://www.ncbi.nlm.nih.gov/pubmed/30713790
http://dx.doi.org/10.1080/2162402X.2018.1534664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343814/
https://www.ncbi.nlm.nih.gov/pubmed/30713790
http://dx.doi.org/10.1080/2162402X.2018.1534664

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