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A variant of the Escherichia coli anaerobic transcription factor FNR exhibiting diminished promoter activation function enhances ionizing radiation resistance
We have previously generated four replicate populations of ionizing radiation (IR)-resistant Escherichia coli though directed evolution. Sequencing of isolates from these populations revealed that mutations affecting DNA repair (through DNA double-strand break repair and replication restart), ROS am...
Autores principales: | Bruckbauer, Steven T., Trimarco, Joseph D., Henry, Camille, Wood, Elizabeth A., Battista, John R., Cox, Michael M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343905/ https://www.ncbi.nlm.nih.gov/pubmed/30673695 http://dx.doi.org/10.1371/journal.pone.0199482 |
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