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regQTLs: Single nucleotide polymorphisms that modulate microRNA regulation of gene expression in tumors

Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with trait diversity and disease susceptibility, yet their functional properties often remain unclear. It has been hypothesized that SNPs in microRNA binding sites may disrupt gene regulation by...

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Detalles Bibliográficos
Autores principales: Wilk, Gary, Braun, Rosemary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343932/
https://www.ncbi.nlm.nih.gov/pubmed/30557297
http://dx.doi.org/10.1371/journal.pgen.1007837