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regQTLs: Single nucleotide polymorphisms that modulate microRNA regulation of gene expression in tumors
Genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with trait diversity and disease susceptibility, yet their functional properties often remain unclear. It has been hypothesized that SNPs in microRNA binding sites may disrupt gene regulation by...
Autores principales: | Wilk, Gary, Braun, Rosemary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343932/ https://www.ncbi.nlm.nih.gov/pubmed/30557297 http://dx.doi.org/10.1371/journal.pgen.1007837 |
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