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Neuroprotective and neuroregenerative effects of CRMP-5 on retinal ganglion cells in an experimental in vivo and in vitro model of glaucoma

PURPOSE: To analyze the potential neuro-protective and neuro-regenerative effects of Collapsin-response-mediator-protein-5 (CRMP-5) on retinal ganglion cells (RGCs) using in vitro and in vivo animal models of glaucoma. METHODS: Elevated intraocular pressure (IOP) was induced in adult female Sprague-...

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Detalles Bibliográficos
Autores principales: Lauzi, Jasmin, Anders, Fabian, Liu, Hanhan, Pfeiffer, Norbert, Grus, Franz, Thanos, Solon, Arnhold, Stefan, Prokosch, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343933/
https://www.ncbi.nlm.nih.gov/pubmed/30673694
http://dx.doi.org/10.1371/journal.pone.0207190