Computational translation of genomic responses from experimental model systems to humans

The high failure rate of therapeutics showing promise in mouse models to translate to patients is a pressing challenge in biomedical science. Though retrospective studies have examined the fidelity of mouse models to their respective human conditions, approaches for prospective translation of insigh...

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Detalles Bibliográficos
Autores principales: Brubaker, Douglas K., Proctor, Elizabeth A., Haigis, Kevin M., Lauffenburger, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343937/
https://www.ncbi.nlm.nih.gov/pubmed/30629591
http://dx.doi.org/10.1371/journal.pcbi.1006286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343937/
https://www.ncbi.nlm.nih.gov/pubmed/30629591
http://dx.doi.org/10.1371/journal.pcbi.1006286

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