CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair

CtIP is involved in the resection of broken DNA during the S and G2 phases of the cell cycle for repair by recombination. Acting with the MRN complex, it plays a particularly important role in handling complex DNA end structures by localised nucleolytic processing of DNA termini in preparation for l...

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Detalles Bibliográficos
Autores principales: Wilkinson, Oliver J, Martín-González, Alejandro, Kang, Haejoo, Northall, Sarah J, Wigley, Dale B, Moreno-Herrero, Fernando, Dillingham, Mark Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344080/
https://www.ncbi.nlm.nih.gov/pubmed/30601117
http://dx.doi.org/10.7554/eLife.42129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344080/
https://www.ncbi.nlm.nih.gov/pubmed/30601117
http://dx.doi.org/10.7554/eLife.42129

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