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CDK4/6 inhibition versus mTOR blockade as second-line strategy in postmenopausal patients with hormone receptor-positive advanced breast cancer: A network meta-analysis

BACKGROUND: Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors (palbociclib and abemaciclib) and mammalian target of rapamycin (mTOR) inhibitors (everolimus) are effective agents for restoring endocrine sensitivity in patients with advanced breast cancer progression on prior aromatase inhibitors. We co...

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Detalles Bibliográficos
Autores principales: Huang, Hong-Wei, Huang, Li-Sheng, Xu, Qi-Ni, Wang, Hong-Biao, Li, Xu-Yuan, Lin, Jia-Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344177/
https://www.ncbi.nlm.nih.gov/pubmed/30608416
http://dx.doi.org/10.1097/MD.0000000000013909