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MicroRNA‐382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells

Proper mitochondrial function plays a central role in cellular metabolism. Various diseases as well as aging are associated with diminished mitochondrial function. Previously, we identified 19 miRNAs putatively involved in the regulation of mitochondrial metabolism in skeletal muscle, a highly metab...

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Detalles Bibliográficos
Autores principales: Dahlmans, Dennis, Houzelle, Alexandre, Andreux, Pénélope, Wang, Xu, Jörgensen, Johanna A., Moullan, Norman, Daemen, Sabine, Kersten, Sander, Auwerx, Johan, Hoeks, Joris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344277/
https://www.ncbi.nlm.nih.gov/pubmed/30417335
http://dx.doi.org/10.1002/jcp.27401