Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution

Conventional human embryonic stem cells are considered to be primed pluripotent but can be induced to enter a naive state. However, the transcriptional features associated with naive and primed pluripotency are still not fully understood. Here we used single-cell RNA sequencing to characterize the d...

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Detalles Bibliográficos
Autores principales: Messmer, Tobias, von Meyenn, Ferdinand, Savino, Aurora, Santos, Fátima, Mohammed, Hisham, Lun, Aaron Tin Long, Marioni, John C., Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344340/
https://www.ncbi.nlm.nih.gov/pubmed/30673604
http://dx.doi.org/10.1016/j.celrep.2018.12.099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344340/
https://www.ncbi.nlm.nih.gov/pubmed/30673604
http://dx.doi.org/10.1016/j.celrep.2018.12.099

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