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The Pituitary Is a Candidate Organ That Modulates Circulating Klotho Levels

CONTEXT: The antiaging protein Klotho is shed and released into the blood stream (soluble Klotho). Growth hormone (GH) is considered an active Klotho regulator, because growth retardation is described in Klotho-deficient mice. The origin of circulating Klotho is, however, not fully understood. OBJEC...

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Detalles Bibliográficos
Autores principales: Sato, Tetsuhiko, Komaba, Hirotaka, Nagatani, Tetsuya, Watanabe, Tadashi, Kishida, Yugo, Fukagawa, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344344/
https://www.ncbi.nlm.nih.gov/pubmed/30697600
http://dx.doi.org/10.1210/js.2018-00223