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The Autoimmune-Associated Single Nucleotide Polymorphism Within PTPN22 Correlates With Clinical Outcome After Lung Transplantation

Obstructive chronic lung allograft dysfunction (BOS) is the major limiting factor for lung transplantation (LTx) outcome. PTPN22 is described as the hallmark autoimmunity gene, and one specific single nucleotide polymorphism (SNP), rs2476601, is associated with multiple autoimmune diseases, impaired...

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Detalles Bibliográficos
Autores principales: Budding, Kevin, van Setten, Jessica, van de Graaf, Eduard A., van Rossum, Oliver A., Kardol-Hoefnagel, Tineke, Kwakkel-van Erp, Johanna M., Oudijk, Erik-Jan D., Hack, C. Erik, Otten, Henderikus G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344400/
https://www.ncbi.nlm.nih.gov/pubmed/30705675
http://dx.doi.org/10.3389/fimmu.2018.03105