Spinal Hyper-Excitability and Altered Muscle Structure Contribute to Muscle Hypertonia in Newborns After Antenatal Hypoxia-Ischemia in a Rabbit Cerebral Palsy Model

Rabbit kits after global antenatal hypoxic-ischemic injury exhibit motor deficits similar to humans with cerebral palsy. We tested several mechanisms previously implicated in spinal hyper-excitability after perinatal brain injury that may explain muscle hypertonia in newborns. Stiffness of hind limb...

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Detalles Bibliográficos
Autores principales: Synowiec, Sylvia, Lu, Jing, Yu, Lei, Goussakov, Ivan, Lieber, Richard, Drobyshevsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344443/
https://www.ncbi.nlm.nih.gov/pubmed/30705663
http://dx.doi.org/10.3389/fneur.2018.01183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344443/
https://www.ncbi.nlm.nih.gov/pubmed/30705663
http://dx.doi.org/10.3389/fneur.2018.01183

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