Lipid Uptake by Alveolar Macrophages Drives Fibrotic Responses to Silica Dust

Silicosis is a common occupational disease and represents a significant contributor to respiratory morbidity and mortality worldwide. Lipid-laden macrophages, or foam cells, are observed in the lungs of patients with silicosis but the mechanisms mediating their formation remain poorly understood. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Xiaomin, Summer, Ross, Chen, Ziying, Tian, Ying, Ma, Jingjing, Cui, Jie, Hao, Xiaohui, Guo, Lingli, Xu, Hong, Wang, Hongli, Liu, Heliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344530/
https://www.ncbi.nlm.nih.gov/pubmed/30674959
http://dx.doi.org/10.1038/s41598-018-36875-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344530/
https://www.ncbi.nlm.nih.gov/pubmed/30674959
http://dx.doi.org/10.1038/s41598-018-36875-2

Ejemplares similares