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SP1 and RARα regulate AGAP2 expression in cancer

AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is considered a proto-oncogene, but not much is known about AGAP2 gene expression regulation. To get some insight into this process, AGAP2 proximal promoter was cloned and characterised using reporter assa...

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Detalles Bibliográficos
Autores principales: Doush, Yegor, Surani, Arif A., Navarro-Corcuera, Amaia, McArdle, Stephanie, Billett, E. Ellen, Montiel-Duarte, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344547/
https://www.ncbi.nlm.nih.gov/pubmed/30674964
http://dx.doi.org/10.1038/s41598-018-36888-x