Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas

Osteosarcomas are characterized by highly disrupted genomes. Although osteosarcomas lack common fusions, we find evidence of many tumour specific gene-gene fusion transcripts, likely due to chromosomal rearrangements and expression of transcription-induced chimeras. Most of the fusions result in out...

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Detalles Bibliográficos
Autores principales: Rathe, Susan K., Popescu, Flavia E., Johnson, James E., Watson, Adrienne L., Marko, Tracy A., Moriarity, Branden S., Ohlfest, John R., Largaespada, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344567/
https://www.ncbi.nlm.nih.gov/pubmed/30674975
http://dx.doi.org/10.1038/s41598-018-36840-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344567/
https://www.ncbi.nlm.nih.gov/pubmed/30674975
http://dx.doi.org/10.1038/s41598-018-36840-z

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