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A VEGF-A/SOX2/SRSF2 network controls VEGFR1 pre-mRNA alternative splicing in lung carcinoma cells

The splice variant sVEGFR1-i13 is a truncated version of the cell membrane-spanning VEGFR1 receptor that is devoid of its transmembrane and tyrosine kinase domains. We recently showed the contribution of sVEGFR1-i13 to the progression and the response of squamous lung carcinoma to anti-angiogenic th...

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Detalles Bibliográficos
Autores principales: Abou Faycal, Cherine, Gazzeri, Sylvie, Eymin, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344584/
https://www.ncbi.nlm.nih.gov/pubmed/30674935
http://dx.doi.org/10.1038/s41598-018-36728-y