Assessing baloxavir susceptibility of influenza viruses circulating in the United States during the 2016/17 and 2017/18 seasons

The anti-influenza therapeutic baloxavir targets cap-dependent endonuclease activity of polymerase acidic (PA) protein. We monitored baloxavir susceptibility in the United States with next generation sequencing analysis supplemented by phenotypic one-cycle infection assay. Analysis of PA sequences o...

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Detalles Bibliográficos
Autores principales: Gubareva, Larisa V, Mishin, Vasiliy P, Patel, Mira C, Chesnokov, Anton, Nguyen, Ha T, De La Cruz, Juan, Spencer, Sarah, Campbell, Angela P, Sinner, Mallory, Reid, Heather, Garten, Rebecca, Katz, Jackie M, Fry, Alicia M, Barnes, John, Wentworth, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2019
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344838/
https://www.ncbi.nlm.nih.gov/pubmed/30670144
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.3.1800666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344838/
https://www.ncbi.nlm.nih.gov/pubmed/30670144
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.3.1800666

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