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MIR sequences recruit zinc finger protein ZNF768 to expressed genes

Mammalian-wide interspersed repeats (MIRs) are retrotransposed elements of mammalian genomes. Here, we report the specific binding of zinc finger protein ZNF768 to the sequence motif GCTGTGTG (N(20)) CCTCTCTG in the core region of MIRs. ZNF768 binding is preferentially associated with euchromatin an...

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Detalles Bibliográficos
Autores principales: Rohrmoser, Michaela, Kluge, Michael, Yahia, Yousra, Gruber-Eber, Anita, Maqbool, Muhammad Ahmad, Forné, Ignasi, Krebs, Stefan, Blum, Helmut, Greifenberg, Ann Katrin, Geyer, Matthias, Descostes, Nicolas, Imhof, Axel, Andrau, Jean-Christophe, Friedel, Caroline C, Eick, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344866/
https://www.ncbi.nlm.nih.gov/pubmed/30476274
http://dx.doi.org/10.1093/nar/gky1148