Excision of uracil from DNA by hSMUG1 includes strand incision and processing

Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. The base excision repair (BER) pathway replaces uracil by the correct base. In...

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Detalles Bibliográficos
Autores principales: Alexeeva, Marina, Moen, Marivi N, Grøsvik, Kristin, Tesfahun, Almaz N, Xu, Xiang Ming, Muruzábal-Lecumberri, Izaskun, Olsen, Kristine M, Rasmussen, Anette, Ruoff, Peter, Kirpekar, Finn, Klungland, Arne, Bjelland, Svein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344882/
https://www.ncbi.nlm.nih.gov/pubmed/30496516
http://dx.doi.org/10.1093/nar/gky1184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344882/
https://www.ncbi.nlm.nih.gov/pubmed/30496516
http://dx.doi.org/10.1093/nar/gky1184

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