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Cerebrospinal fluid levels of glial marker YKL-40 strongly associated with axonal injury in HIV infection
BACKGROUND: HIV-1 infects the central nervous system (CNS) shortly after transmission. This leads to a chronic intrathecal immune activation. YKL-40, a biomarker that mainly reflects activation of astroglial cells, has not been thoroughly investigated in relation to HIV. The objective of our study w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345016/ https://www.ncbi.nlm.nih.gov/pubmed/30678707 http://dx.doi.org/10.1186/s12974-019-1404-9 |