Cargando…

CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes

BACKGROUND: Systemic inflammation and the fever response to pathogens are coordinately regulated by IL-6 and IL-1β. We previously showed that CEACAM1 regulates the LPS driven expression of IL-1β in murine neutrophils through its ITIM receptor. RESULTS: We now show that the prompt secretion of IL-6 i...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhifang, La Placa, Deirdre, Nguyen, Tung, Kujawski, Maciej, Le, Keith, Li, Lin, Shively, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345024/
https://www.ncbi.nlm.nih.gov/pubmed/30674283
http://dx.doi.org/10.1186/s12865-019-0287-y