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CEACAM1 regulates the IL-6 mediated fever response to LPS through the RP105 receptor in murine monocytes
BACKGROUND: Systemic inflammation and the fever response to pathogens are coordinately regulated by IL-6 and IL-1β. We previously showed that CEACAM1 regulates the LPS driven expression of IL-1β in murine neutrophils through its ITIM receptor. RESULTS: We now show that the prompt secretion of IL-6 i...
Autores principales: | Zhang, Zhifang, La Placa, Deirdre, Nguyen, Tung, Kujawski, Maciej, Le, Keith, Li, Lin, Shively, John E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345024/ https://www.ncbi.nlm.nih.gov/pubmed/30674283 http://dx.doi.org/10.1186/s12865-019-0287-y |
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