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Dilated cardiomyopathy-mediated heart failure induces a unique skeletal muscle myopathy with inflammation

BACKGROUND: Skeletal muscle myopathy and exercise intolerance are diagnostic hallmarks of heart failure (HF). However, the molecular adaptations of skeletal muscles during dilated cardiomyopathy (DCM)-mediated HF are not completely understood. METHODS: Skeletal muscle structure and function were com...

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Detalles Bibliográficos
Autores principales: Song, Taejeong, Manoharan, Palanikumar, Millay, Douglas P., Koch, Sheryl E., Rubinstein, Jack, Heiny, Judith A., Sadayappan, Sakthivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345027/
https://www.ncbi.nlm.nih.gov/pubmed/30678732
http://dx.doi.org/10.1186/s13395-019-0189-y