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The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer

BACKGROUND: The role of tumor protein D54 in breast cancer has not been studied and its function in breast cancer remains unclear. In our previous pharmacogenomic studies using lymphoblastoid cell line (LCL), this protein has been identified to affect metformin response. Although metformin has been...

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Detalles Bibliográficos
Autores principales: Zhuang, Yongxian, Ly, Reynold C., Frazier, Carleigh V., Yu, Jia, Qin, Sisi, Fan, Xiao-Yang, Goetz, Matthew P., Boughey, Judy C., Weinshilboum, Richard, Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345044/
https://www.ncbi.nlm.nih.gov/pubmed/30697423
http://dx.doi.org/10.1186/s40170-018-0193-4