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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14

BACKGROUND: Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA interference (RNAi)-based targeted gene silencing is a quick,...

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Detalles Bibliográficos
Autores principales: Ervin, Egle-Helene, Pook, Martin, Teino, Indrek, Kasuk, Valmar, Trei, Annika, Pooga, Margus, Maimets, Toivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345057/
https://www.ncbi.nlm.nih.gov/pubmed/30678718
http://dx.doi.org/10.1186/s13287-019-1144-x