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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14
BACKGROUND: Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA interference (RNAi)-based targeted gene silencing is a quick,...
Autores principales: | Ervin, Egle-Helene, Pook, Martin, Teino, Indrek, Kasuk, Valmar, Trei, Annika, Pooga, Margus, Maimets, Toivo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345057/ https://www.ncbi.nlm.nih.gov/pubmed/30678718 http://dx.doi.org/10.1186/s13287-019-1144-x |
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