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Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca(V)2.1 and Ca(V)2.2 in Rat Midbrain Neurons

Volatile anesthetics affect neuronal signaling by poorly understood mechanisms. Activation of central dopaminergic pathways has been implicated in emergence from general anesthesia. The volatile anesthetic isoflurane differentially inhibits glutamatergic and GABAergic synaptic vesicle (SV) exocytosi...

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Detalles Bibliográficos
Autores principales: Torturo, Christina L., Zhou, Zhen-Yu, Ryan, Timothy A., Hemmings, Hugh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345200/
https://www.ncbi.nlm.nih.gov/pubmed/30680310
http://dx.doi.org/10.1523/ENEURO.0278-18.2018