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Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme

[Image: see text] Detoxifying enzymes such as flavin-containing monooxygenases deal with a huge array of highly diverse xenobiotics and toxic compounds. In addition to being of high physiological relevance, these drug-metabolizing enzymes are useful catalysts for synthetic chemistry. Despite the wea...

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Detalles Bibliográficos
Autores principales: Fürst, Maximilian J. L. J., Romero, Elvira, Gómez Castellanos, J. Rúben, Fraaije, Marco W., Mattevi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345240/
https://www.ncbi.nlm.nih.gov/pubmed/30687578
http://dx.doi.org/10.1021/acscatal.8b03793